Search on: SERRATE-JAGGED PROTEINS 
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Descriptor English:   Serrate-Jagged Proteins 
Descriptor Spanish:   Proteínas Serrate-Jagged 
Descriptor Portuguese:   Proteínas Serrate-Jagged 
Synonyms English:   Jagged Proteins
Serrate Protein
Serrate Proteins
Serrate Jagged Proteins  
Tree Number:   D12.644.276.930
D12.776.157.125.797
D12.776.543.800
D23.529.930
Definition English:   Cell surface proteins that consist of multiple extracellular EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats), including calcium-binding EGF repeats. They function as transmembrane ligands for NOTCH RECEPTORS to control CELL DIFFERENTIATION during development. 
History Note English:   2017 (1991) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56529 
Unique Identifier:   D000072099 

Occurrence in VHL:
 

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